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NCT07335107Possibly a fitNot yet recruiting

Tirofiban after bridging therapy for acute stroke due to large artery blockage

Acute Ischemic Stroke

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests whether adding a medicine called tirofiban (which helps prevent blood clots) after standard stroke treatment can improve recovery in people who had a stroke due to a blocked large artery in the brain. It is for people who already received a clot-busting drug and a mechanical clot removal procedure, and who have not fully recovered.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
564 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years old or older.
  • You must have a recent stroke (within 24 hours) that was treated with a clot-busting drug followed by a mechanical clot removal procedure (called bridging therapy).
  • The stroke must be caused by a blockage in a large artery in your neck or brain, likely due to hardening of the arteries (atherosclerosis), not by a blood clot that traveled from the heart.
  • You must not have a known history of atrial fibrillation (a type of irregular heartbeat).
  • After the clot removal procedure, your blood flow must have been successfully restored, but you may still have some narrowing in the artery.
  • You must not have any serious bleeding conditions, severe kidney or liver disease, recent heart problems, or active cancer that would limit your life expectancy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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