Early antiplatelet after clot-busting for stroke (TREND-IVT)
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving an antiplatelet medicine (like aspirin) early—within 3 hours of a clot-busting drug—can help prevent another stroke without causing bleeding. It is for people who still have moderate to severe stroke symptoms after the clot-buster and do not have a large artery blockage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke and received a clot-busting medicine (alteplase or tenecteplase) within 4.5 hours of symptoms starting.
- One hour after the clot-buster, your stroke symptoms are still moderate to severe (NIHSS score >5).
- You do not have a large artery blockage needing a separate clot removal procedure.
- You have not taken antiplatelet medicine (like aspirin or clopidogrel) in the week before your stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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