Preventing first bleeding from varices in liver cancer patients
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial compares two treatments (banding or a medication called carvedilol) to prevent the first episode of bleeding from enlarged veins in the esophagus in people with liver cancer. The goal is to find which approach is safer and more effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with liver cancer (HCC).
- You have medium to large varices (F2 or F3) in your esophagus that haven't bled yet.
- You are between 20 and 90 years old.
- You have not had any treatment for varices before, such as banding, sclerotherapy, or a shunt procedure.
- You have not taken beta-blocker medication (like carvedilol) in the last two weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding endoscopic banding helps prevent bleeding from enlarged varices in people with cirrhosis who still have high-risk varices despite taking carvedilol.
This trial compares two ways to prevent bleeding from enlarged veins in the food pipe (esophageal varices) in people with cirrhosis. It tests whether carvedilol (a blood-pressure/heart medicine) works as well as an endoscopic procedure that places small bands to reduce bleeding risk.
This trial tests if preventing esophageal varices (swollen veins in the food pipe) can reduce bleeding risk in people with advanced liver cancer who are receiving a combination of two drugs (atezolizumab and bevacizumab). It may help those with good liver function and no high-risk varices at the start.
This trial compares two approaches to prevent future bleeding from enlarged veins in the esophagus (food pipe) in patients with liver cirrhosis who have already had one bleeding episode. You'll receive either an endoscopic procedure with medication or a minimally invasive vein procedure, to see which works better long-term.
This trial compares two different ways of using rubber bands to treat swollen veins in the food pipe (varices) caused by cirrhosis. It aims to find which method is better at preventing first-time bleeding.
This study looks at how to best use endoscopy and other procedures to stop bleeding from enlarged veins in the esophagus or stomach caused by liver disease. It aims to find the safest and most effective treatment approach for people with this condition.
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