Inhaled antibiotic for lung infection during ECMO support
Treatments studied
Part of Infections, Lungs & breathing clinical trials.
This trial tests whether adding an inhaled antibiotic (amikacin) to standard IV antibiotics can better treat a serious lung infection (pneumonia caused by Gram-negative bacteria) in patients on a heart-lung machine (ECMO) and a breathing tube. If you or your loved one is on ECMO and has this type of pneumonia, this study may offer a new treatment approach.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been on a heart-lung machine (ECMO) for at least 24 hours before the pneumonia was found.
- You are on a breathing machine (ventilator) and have signs of pneumonia (such as fever, low blood oxygen, or new chest X-ray changes).
- A sample from your lungs tested positive for Gram-negative bacteria (a common type of infection).
- You are already receiving a specific IV antibiotic (piperacillin-tazobactam) as part of your treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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