CPAP on ECMO for severe lung failure
Part of Lungs & breathing clinical trials.
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be on a breathing machine called VV-ECMO for severe lung failure within the last 48 hours.
- You cannot have had a long cardiac arrest (more than 10 minutes) before starting ECMO.
- You must not have untreated air leaks in your chest (like a collapsed lung) or serious lung injury from high pressure.
- You cannot be in another study that looks at the same main outcomes (like survival or lung transplant).
- You must be at least 18 years old and not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
This trial tests a full-course strategy using a heart-lung bypass machine (ECMO) for people with moderate-to-severe acute respiratory distress syndrome (ARDS), a serious lung condition. The goal is to see if starting and continuing ECMO throughout treatment improves recovery.
This trial compares starting ECMO early versus later in adults with severe lung failure (ARDS). It tests whether starting the life-support machine sooner can improve outcomes by the time doctors need it.
This study looks at inflammation during ECMO (a heart-lung bypass machine) and while people are being weaned off it. It may help doctors better understand which patients are improving safely during ECMO and when to reduce support.
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
Hear when a new Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.