Clin2
NCT06613217Possibly a fitRecruiting

Oral PCLX-001 for relapsed or refractory AML

Relapsed Adult AML

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests an oral drug called PCLX-001 for people with acute myeloid leukemia (AML) that has come back or not responded to previous treatments. The goal is to see if the drug is safe and can help control the leukemia.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
35 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older with a confirmed diagnosis of acute myeloid leukemia (AML).
  • You must have had at least one prior treatment for AML, and no other standard therapies are expected to help you.
  • You should be generally active (able to care for yourself, up and about more than half the day).
  • Your liver and kidney function must be within a certain range (checked by blood tests).
  • You must be able to swallow oral medication and not have a condition that affects absorption.
  • If you are of childbearing potential, you must agree to use effective contraception during and for 6 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06285890Recruiting· Phase 1
HC-7366 study for relapsed or refractory AML

This trial tests a new drug called HC-7366 for people whose acute myeloid leukemia (AML) has come back or hasn't responded to treatment. It aims to see if this drug is safe and helpful when standard options are no longer working.

Houston, Texas
NCT07549464Not yet recruiting· Phase 1
PLM-102 for leukemia that has come back or not responded

This phase 1 trial tests a new drug called PLM-102 for people with acute myeloid leukemia (AML) that has come back or hasn't responded to standard treatment. The goal is to find the best dose and see if it can help control the leukemia.

Houston, Texas
NCT04774393Recruiting· Phase 1/Phase 2
Study for AML after it returns or resists treatment

This Phase 1/2 trial tests a combination of medicines (decitabine/cedazuridine, venetoclax, and ivosidenib or enasidenib) in people with acute myeloid leukemia (AML) that has come back or hasn’t responded. It may help control the leukemia by targeting cancer cells and specific genetic changes in the leukemia.

Houston, Texas
NCT05703542Recruiting· Phase 1
Testing BXCL701 for relapsed or resistant AML or MDS

This Phase 1 study tests BXCL701 in adults whose acute myeloid leukemia (AML) or high-blast myelodysplastic syndrome (MDS-EB-2) has come back or not responded to prior treatment. The goal is to find a safe dose and see how the treatment affects cancer cells.

Boston, Massachusetts
NCT05143996Recruiting· Phase 1
First study drug for relapsed AML or MDS

This Phase 1 trial tests CLN-049 in adults whose acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) has come back or did not respond to treatment. The goal is to find out how well the drug can work and how safe it is in people with limited options.

Birmingham, Alabama
NCT06265545Recruiting
Study for relapsed or hard-to-treat AML

This trial tests new treatment options for people whose acute myeloid leukemia (AML) has either not responded to standard therapy or returned. It aims to find better ways to help those who need new options.

Tianjin

Hear when a new Relapsed Adult AML trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.