Clin2
NCT06622057Possibly a fitRecruiting

D07001 and capecitabine for advanced bile duct cancer

Biliary Tract Cancer (BTC)

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of two oral medications, D07001 and capecitabine, for people with advanced bile duct, gallbladder, or ampullary cancer that has gotten worse after standard chemotherapy. The goal is to see if this combination can help control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have advanced bile duct, gallbladder, or ampullary cancer that cannot be removed by surgery or has spread.
  • Your cancer has progressed after treatment with gemcitabine and cisplatin (or similar chemotherapy).
  • Your cancer can be measured on scans (RECIST criteria).
  • You are willing to use birth control if needed and follow the study schedule.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07745296Not yet recruiting· Phase 3
Precision medicine after surgery for bile duct cancer

This trial tests whether matching targeted therapy to the genetic changes in your cancer can lower the chance of it coming back after surgery. You would first have your tumor tested for specific alterations, and if one is found, you may receive a drug that targets it.

NCT07733115Recruiting· Phase 2
Drug combo for advanced bile duct cancer

This trial tests a new immunotherapy drug combined with standard chemotherapy as a first treatment for advanced bile duct or gallbladder cancer. It may help your immune system fight the cancer while chemotherapy attacks the tumor directly.

Shanghai
NCT05065957Recruiting· Phase 2/Phase 3
Study of two oral chemo medicines for advanced bile duct cancer

This trial tests a combination of two oral chemotherapy medicines (D07001 softgel plus Xeloda/TS-1) in people with advanced bile duct tract cancer that can’t be removed by surgery. It’s for situations where first-line gemcitabine plus cisplatin chemotherapy no longer worked.

Kaohsiung City
NCT05849480Recruiting· Phase 1/Phase 2
Study of CD40 treatment with CAPOX and Keytruda for bile duct cancer

This trial studies a new immune “switch” treatment called CDX-1140 combined with standard chemo (CAPOX) and Keytruda, for biliary tract cancer that can’t be cured with surgery or transplant. It’s designed for people whose cancer has progressed after first-line treatment, with the goal of improving cancer control and outcomes.

Bethesda, Maryland
NCT06463548Not yet recruiting
Drug combo for advanced bile duct cancer after first treatment

This trial tests a combination of three drugs (irinotecan liposome, capecitabine, and lenvatinib) for people with advanced bile duct or gallbladder cancer that has worsened after one prior treatment. It may be an option if you haven't taken capecitabine or lenvatinib before and are generally feeling well.

Shenyang
NCT07729917Not yet recruiting· Phase 2
Precision trial for biliary tract cancers

This trial tests different treatments for advanced bile duct or gallbladder cancer based on individual tumor features. It may help people who have not had prior therapy for their cancer.

Hangzhou, Zhejiang

Hear when a new Biliary Tract Cancer (BTC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.