Testing LPX-TI641 for rheumatoid and psoriatic arthritis
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This trial tests a new drug, LPX-TI641, to see if it is safe and how it works in the body for people with rheumatoid arthritis or psoriatic arthritis. It may be an option if you have active joint swelling and pain despite standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older with a body mass index between 18 and 35.
- You have rheumatoid arthritis diagnosed at least 3 months ago with at least 6 tender and 6 swollen joints, or psoriatic arthritis with at least 3 tender and 3 swollen joints plus a psoriasis patch.
- You have been on a stable dose of a standard disease-modifying drug (like methotrexate or sulfasalazine) for at least 4 weeks, or you cannot tolerate these drugs.
- You must not have taken certain other arthritis drugs or treatments, including biologics, JAK inhibitors, or cell-depleting therapies, within a specific time frame.
- Women who can become pregnant must use two highly effective birth control methods; men must also use birth control with their partners.
- You must be in generally good health with no active infections, cancer in the last 5 years (except treated skin cancer), or tuberculosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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