Preventing kidney worsening with IV albumin in heart failure
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if giving a medicine called albumin through a vein can help prevent kidney function from getting worse in people hospitalized with worsening heart failure and liver problems. It may be an option if other treatments haven't worked.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are in the hospital because your chronic heart failure suddenly worsened.
- You have liver problems caused by your heart failure (not by other conditions like alcohol).
- You have taken a loop diuretic (water pill like furosemide) by mouth in the past.
- Doctors expect you will need IV diuretics (water pills given through a vein) for at least 3 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial studies two ways of giving albumin (a protein given through an IV) to people with cirrhosis who also have a sudden kidney injury from sepsis. The goal is to see which method—tailored to each patient or a fixed dose—is safer and works better for kidney recovery.
This study tests whether giving albumin through a vein helps people with cirrhosis who have a certain type of kidney problem (called acute kidney injury). The goal is to see if albumin works better than a simple saltwater solution in improving kidney function.
This trial tests whether giving albumin (a blood protein through an IV) can improve recovery after acute kidney injury in people who are in the ICU and need kidney support treatment. It mainly aims to help the kidneys bounce back better after this serious illness.
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
This study tests whether giving albumin (a protein) along with water pills helps reduce leg swelling in people with cirrhosis and ascites. It may be an option if your leg swelling hasn't improved with standard diuretics alone.
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