Study of new drug MEN2312 for advanced breast cancer with specific genetic changes
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug, MEN2312, for people with advanced breast cancer that has specific genetic changes in PIK3CA, AKT1, or PTEN. It's for those who have already tried certain hormone therapies and a CDK4/6 inhibitor combination, and the cancer has continued to grow.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced breast cancer that cannot be cured with standard treatments.
- Your tumor has specific genetic changes in PIK3CA, AKT1, or PTEN.
- You have already had at least one type of hormone therapy for advanced cancer, or your cancer returned within 12 months after finishing hormone treatment after surgery.
- Your cancer got worse while you were taking a CDK4/6 inhibitor pill combined with either fulvestrant or an aromatase inhibitor.
- You do not have active or newly diagnosed cancer that has spread to the brain.
- You have recovered from side effects of previous radiation therapy, except hair loss and mild numbness or tingling in hands or feet.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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