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NCT06641414Possibly a fitRecruiting

Lisaftoclax with azacytidine for higher-risk myelodysplastic syndrome

Higher-risk Myelodysplastic Syndrome

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new drug called lisaftoclax combined with a standard treatment, azacytidine, for people newly diagnosed with higher-risk myelodysplastic syndrome (MDS). The goal is to see if the combination helps control the disease better than what's currently available.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
490 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be newly diagnosed with higher-risk myelodysplastic syndrome (MDS).
  • You should be able to perform daily activities with some help (ECOG score 0-2).
  • Your life expectancy should be at least 3 months.
  • Your organs must be working well enough to receive the treatment.
  • If you can become pregnant, you must have a negative pregnancy test and use effective birth control during treatment and for 6 months after.
  • You must be able to understand and sign a consent form.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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