Clin2
NCT06641661Possibly a fitNot yet recruiting

Gene-guided cholesterol lowering for high-risk patients

Gene PolymorphismASCVD

Part of Cancer clinical trials.

This study looks at how your genes affect a new medicine that helps lower cholesterol when statins alone aren't enough. If you join, you'll add this medicine to your current statin to see if it helps you reach your cholesterol goals.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,000 people
Ages
18 years to 75 years
Study type
Observational

Who can take part

  • You are between 18 and 75 years old.
  • You have been taking a moderate-dose statin (like atorvastatin or rosuvastatin) for at least 8 weeks.
  • Your LDL (bad) cholesterol is still not at the target level despite the statin.
  • You are not allergic to statins or cholesterol absorption inhibitors.
  • You do not have severe liver or kidney problems, active cancer, thyroid issues, or other serious conditions.
  • You are not pregnant or planning pregnancy, and you can commit to regular follow-ups.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06568471Recruiting· Phase 3
Study of HST101 for high cholesterol in Chinese patients

This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.

Beijing, Beijing Municipality
NCT06125847Recruiting· Early Phase 1
Gene therapy for inherited high cholesterol

This trial tests a one-time gene therapy to lower extremely high cholesterol in people with a rare inherited condition. It may help reduce heart attack risk in those who haven't responded to standard treatments.

Xi'an, Shaanxi
NCT07615296Not yet recruiting
Comparing two very low cholesterol targets for high-risk heart patients

This trial compares two very low LDL-cholesterol targets (below 1.0 vs 1.0-1.39 mmol/L) using extra medications (PCSK9 inhibitors) to see which is safer and better for people at extremely high risk of heart attacks or strokes.

Beijing, Beijing Municipality
NCT07421284Not yet recruiting· Phase 3
New cholesterol-lowering medication for high cholesterol

This study tests a new medication called SYH2053 to see if it helps lower 'bad' cholesterol more effectively when added to your current statin therapy. It is for patients whose cholesterol is still not at their doctor's target level, and it aims to improve heart health.

Beijing, Beijing Municipality
NCT06750341Not yet recruiting· Phase 2
Study of a new drug for high cholesterol

This study tests an experimental drug (QLC7401) that may help lower LDL ('bad') cholesterol in people who already have high cholesterol or mixed hyperlipidemia. If you're on stable cholesterol medication but still need more lowering, this trial could offer another option.

NCT06293729Not yet recruiting· Early Phase 1
Gene therapy for inherited high cholesterol

This trial tests a new gene therapy called NGGT006 for people with a genetic form of high cholesterol that doesn't improve with standard treatments. It aims to lower cholesterol levels and reduce the risk of heart problems.

Hear when a new ASCVD trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.