Clin2
NCT07421284Possibly a fitNot yet recruiting

Study of SYH2053 for high cholesterol in Chinese adults

Non-familial Hypercholesterolemia and Mixed Hyperlipidemia

Part of Genetic & congenital, Hormones & metabolism clinical trials.

This trial tests a new investigational medicine (SYH2053) for people with high cholesterol or mixed hyperlipidemia who are already on cholesterol-lowering therapy but still have high levels of 'bad cholesterol' (LDL-C). The goal is to see if this add-on treatment can help lower cholesterol further and reduce heart disease risk.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
900 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old
  • You have been on a stable dose of cholesterol-lowering therapy (like a statin, with or without other medicines) for at least 4 weeks
  • Your 'bad cholesterol' (LDL-C) is still not at your target level based on your heart disease risk
  • You do not have familial hypercholesterolemia (inherited very high cholesterol), serious liver or kidney disease, or uncontrolled high blood pressure
  • You have not taken certain newer cholesterol drugs (like PCSK9 inhibitors or Inclisiran) in the past 6 months to 2 years
  • You do not have a history of cancer (except treated skin cancer) in the last 5 years or other serious health conditions

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07421297Recruiting· Phase 3
Study of SYH2053 for high cholesterol in Chinese adults

This trial tests a new medication called SYH2053 for people with high cholesterol or mixed high cholesterol and triglycerides. If you have high LDL cholesterol and are not taking strong cholesterol medicines, you may be able to join. The study will see if this drug is safe and works well.

Beijing, Beijing Municipality
NCT07465263Recruiting· Phase 3
Study of SYH2053 Injection for High Cholesterol in HeFH

This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.

Beijing, Beijing Municipality
NCT06568471Recruiting· Phase 3
Study of HST101 for high cholesterol in Chinese patients

This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.

Beijing, Beijing Municipality
NCT05621070Recruiting· Phase 3
Test drug JS002 for high cholesterol not at goal

This Phase 3 study tests whether JS002 alone can lower LDL “bad” cholesterol in people whose levels are still too high for their heart-risk level. It will also check how safe the treatment is, especially for heart and metabolic side effects.

Beijing, Beijing Municipality
NCT07695597Recruiting· Phase 2
Study of SYH2070 for people with high cholesterol and triglycerides

This trial tests an investigational injection called SYH2070 to lower cholesterol and triglycerides in people who are already on a stable statin therapy. It may be a new option for those with mixed hyperlipidemia who need additional lipid control.

Hangzhou, Zhejiang
NCT07241923Recruiting· Phase 1
SYH2070 injection safety study for high triglycerides and high cholesterol

This study tests a new injection called SYH2070 for people with high triglycerides and high LDL cholesterol. The goal is to see if a single dose is safe and how the body processes the medication. It is for people who have not been on cholesterol-lowering drugs recently.

Shijiazhuang, Hebei

Hear when a new Non-familial Hypercholesterolemia and Mixed Hyperlipidemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.