Study of HST101 for high cholesterol in Chinese patients
Treatments studied
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You weigh at least 40 kg (88 lbs) and your BMI is between 18 and 35.
- You have been on a stable dose of cholesterol-lowering pills (like statins) for at least 4 weeks.
- You have a history of heart disease, stroke, or are at high risk, and your LDL cholesterol is high enough and triglycerides are not too high.
- You do not have severe kidney disease, poorly controlled diabetes, or recent heart events.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new drug, HST101, to see if it is safe for healthy Chinese people with high cholesterol. It is an early-phase trial, so it focuses on safety first.
This trial tests a new cholesterol-lowering drug called Hybutimibe for people who are already taking a moderate-dose statin but still have high LDL (bad) cholesterol. It aims to see how well the drug works based on your genes.
This trial tests a new injection called ART002g1 for people with a genetic condition that causes very high cholesterol. It aims to see if the drug is safe and can help lower cholesterol levels.
This trial tests a new medicine, CTX310, for people with persistently high levels of fats (triglycerides) and cholesterol that have not improved with standard treatments. It aims to see if the drug is safe and tolerable.
This trial tests a new medicine, SHR-1918, for people whose bad cholesterol (LDL-C) stays high even when they take statins and another type of cholesterol-lowering drug called a PCSK9 inhibitor. It aims to see if this additional treatment can lower their cholesterol more effectively.
This trial tests a new investigational medicine (SYH2053) for people with high cholesterol or mixed hyperlipidemia who are already on cholesterol-lowering therapy but still have high levels of 'bad cholesterol' (LDL-C). The goal is to see if this add-on treatment can help lower cholesterol further and reduce heart disease risk.
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