Clinical trials
ASCVD clinical trials
Below are recruiting ascvd clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06691217RecruitingPhase 2
Testing an Anti-Inflammatory Drug for Heart Disease With TET2 Mutation
This study tests whether a medication that blocks inflammation (called an IL-1 beta inhibitor) can reduce blood vessel inflammation in people with both heart disease and a specific genetic change in their blood cells (TET2 mutation). It aims to see if targeting this type of inflammation can help lower heart risks.
Boston, MassachusettsAges 18 years+ - NCT07464574Recruiting
Lowering cholesterol with non-statin drugs
This study tests if adding non-statin medications can help people with heart or blood vessel disease who still have high cholesterol despite taking statins. It aims to get their LDL (bad) cholesterol to a safer level.
Austin, TexasAges 18 years+ - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT06813911RecruitingPhase 3
Testing pelacarsen for high Lp(a) in heart disease patients
This trial tests a new medicine called pelacarsen for people with very high Lp(a) (a type of cholesterol) and existing heart or blood vessel disease. It aims to see if adding pelacarsen to your current cholesterol treatment can lower your Lp(a) levels further.
Birmingham, AlabamaAges 18–80 - NCT06960655Enrolling by invitation
Improving heart disease treatment and cholesterol care
This program aims to improve how doctors manage cholesterol and other treatments for people with heart or blood vessel disease. It focuses on patients who also have diabetes or a genetic high-cholesterol condition, and are seen at Mass General Brigham.
Boston, MassachusettsAges 18–95 - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Apache Junction, ArizonaAges 18 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Huntsville, AlabamaAges 40–80 - NCT07270887Recruiting
Can gentle arm cuffs protect your heart and brain over time?
This trial tests if using a blood pressure cuff on your arm in short cycles can help prevent future heart attacks, strokes, and other problems in people at very high risk. You may qualify if you've already had a major heart or blood vessel event.
ShenyangAges 40 years+ - NCT07327840RecruitingPhase 2
Study of Kylo-11 for heart disease with high Lp(a)
This trial tests a new drug, Kylo-11, for people with heart or blood vessel disease and high Lp(a), a type of cholesterol that raises risk of heart problems. The study will see if Kylo-11 can help lower that risk.
Los Angeles, CaliforniaAges 18–80 - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT05611307Recruiting
Heart Health in Testicular Cancer Survivors
This study looks at heart health in men who have survived testicular cancer. It compares those who had different treatments (surgery, chemotherapy, or chemotherapy plus a stem cell transplant) to see if there are hidden signs of heart or blood vessel problems.
Indianapolis, IndianaAges 18–99 - NCT06471036Recruiting
Improving cholesterol testing and treatment after a heart attack
This study tests whether giving extra education to doctors and patients can help improve cholesterol management after a heart-related hospitalization. It aims to see if a simple program can make sure patients get the right testing and treatment for high cholesterol.
Minneapolis, MinnesotaAges 18 years+ - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT05765370Recruiting
LDL cholesterol study in people 75+ with heart or blood vessel disease
This trial studies how to lower “bad” cholesterol (LDL) in people age 75 and older who have already had heart, brain, or leg/blood-vessel problems from blocked arteries. The goal is to see if the approach helps prevent further cardiovascular events (like heart attack or stroke).
Beijing, Beijing MunicipalityAges 75 years+ - NCT05879913Recruiting
Heart risk check using CT scan in men on prostate cancer therapy
This study looks at how a special CT heart scan (CCTA) can help manage heart disease risk in men with prostate cancer who are taking hormone therapy (ADT). It may help your care team better assess heart risk, especially if you also have other heart risk factors but no current heart symptoms.
Carmel, IndianaAges 40 years+ - NCT06568471RecruitingPhase 3
Study of HST101 for high cholesterol in Chinese patients
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06767774RecruitingPhase 4
Comparing two cholesterol treatments for heart patients
This study compares two different ways of lowering cholesterol: a moderate statin (pitavastatin) plus another drug (ezetimibe) versus a stronger statin alone. The goal is to see which approach is safer regarding the risk of developing new diabetes.
SeoulAges 18 years+ - NCT06930885RecruitingPhase 3
Polypill and colchicine for heart and artery risk
This trial tests a combination pill (polypill) and a medicine called colchicine to see if they can lower the risk of future heart attacks, strokes, or other artery problems. It is for people who already have a history of heart or blood vessel disease.
Maceió, AlabamaAges 45 years+ - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Athens, AlabamaAges 18 years+ - NCT07487363RecruitingPhase 1/Phase 2
TB-500 for heart health in stable artery disease
This study tests if TB-500 can improve blood markers of cardiovascular health in people with stable artery disease. It is an early-phase trial to see if the drug is safe and shows promise.
Shenzhen, GuangdongAges 40–75 - NCT07524101Recruiting
Statin and Ezetimibe for Heart Disease and Kidney Disease
This trial tests whether taking a moderate-strength statin (cholesterol-lowering drug) plus ezetimibe (another cholesterol medicine) together helps protect the heart and kidneys in people who have both chronic kidney disease and established heart disease or stroke history.
SeoulAges 19–85 - NCT07542860Recruiting
Comparing two aspirin doses in older heart disease patients
This study compares whether a lower dose of aspirin (50 mg) works as well as a standard dose (100 mg) for older adults who have had heart attacks, strokes, or other heart and blood vessel problems. The goal is to find the safest effective dose to prevent future events.
BeijingAges 60 years+ - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+
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ASCVD trials by city
Studies with a site in or near these metro areas.
ASCVD trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for ascvd?
- Yes. Clin2 currently lists 25 recruiting ascvd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ascvd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ascvd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.