Denosumab for muscle loss in older adults with osteoporosis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether a drug called Denosumab, which is used to treat bone loss, can also help improve muscle strength and mass in older adults who have both osteoporosis and sarcopenia. If you qualify, you would receive the drug and be monitored over time to see if it helps your bones and muscles.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older
- You have been diagnosed with both osteoporosis (low bone density) and sarcopenia (low muscle mass and strength)
- You have not had a broken bone in the last 3 months
- You have not taken any osteoporosis medication before
- You are able to walk and stand on your own (not wheelchair-bound or bedbound)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a drug that blocks a protein called RANKL can help older adults regain muscle mass and strength after a hip fracture surgery. It is for people 65 and older who have sarcopenia (muscle loss) and broke their hip from a simple fall.
This trial tests an investigational drug called AMC6156 to see if it can help improve muscle mass and strength in older adults with sarcopenia (age-related muscle loss). Participants will also follow exercise and nutrition guidance.
This study tests whether exercise and nutrition can help prevent bone weakening and muscle loss in middle-aged adults. You'll participate in a prevention program designed to keep your bones and muscles strong as you age.
This trial is for adults with chronic kidney disease and low muscle strength (sarcopenia). It aims to find ways to improve outcomes, especially if you have a higher risk of complications.
This study tests whether an osteoporosis medication can help preserve muscle strength in older adults who live in senior facilities. It's for people age 65+ with fragile bones or low bone density who are at risk for falls and fractures.
This study tests whether denosumab, a medication that strengthens bones, can also improve muscle strength and insulin sensitivity in postmenopausal women with type 2 diabetes who take metformin.
Hear when a new Sarcopenia in Elderly trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.