Clin2
NCT06647498Possibly a fitRecruiting

Study of a treatment for early-onset Alzheimer's caused by a gene change

Alzheimers DiseaseDementiaAlzheimers Disease, Familial

Part of Brain & nervous system, Mental health clinical trials.

This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
280 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You carry a mutation in the APP, PSEN1, or PSEN2 gene (or your family has such a mutation, and you might have it too).
  • You are between 25 and 11 years before the expected age of symptom onset based on your family history.
  • You have a study partner who can help provide information about you during the study.
  • You agree to not become pregnant or get someone pregnant and use highly effective birth control during the study and for 20 weeks after the last dose.
  • You do not have significant other brain or health conditions that would interfere with the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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