Study of vaginal health after stem cell transplant
Part of Immune system & allergy clinical trials.
This study looks at how stem cell transplants affect the vagina, especially if you develop a condition called graft-versus-host disease (GVHD). Researchers will examine the vagina and test its natural germs (microbiome) to better understand and possibly improve treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are female and between 18 and 70 years old.
- You have had or are planning to have a stem cell transplant (HCT).
- You are willing to have a vaginal exam as part of the study.
- You do not currently have an untreated sexually transmitted infection (STI) like herpes, chlamydia, or gonorrhea.
- You do not have a history of certain vaginal skin conditions (lichen sclerosus or lichen planus) before transplant.
- You have never had vaginal or vulvar cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial checks if measuring a specific virus marker in your blood after a stem cell transplant can help predict or prevent transplant complications. You would have extra blood tests to guide your care.
This study tests a combination of three drugs—high-dose cyclophosphamide, bortezomib, and abatacept—after a donor stem cell transplant to see if they can better prevent graft-versus-host disease (a condition where donor cells attack the body).
This Phase 1 study tests a new combination of medicines to prevent graft-versus-host disease (GVHD) after an allogeneic stem cell transplant. If it works well, it may lower the chance and severity of GVHD, which can affect skin, liver, and the gut.
This observational study follows people who had a stem cell transplant a few months ago to better understand risk for chronic graft-versus-host disease. You won’t get a study treatment; instead, you’ll complete questionnaires over time, and the study team looks at your symptoms and experiences.
This study looks at immune cells in the blood and tissues of people who have had a stem cell transplant. It aims to understand chronic graft-versus-host disease (GVHD), a common complication, so doctors can better detect and treat it.
This study looks at improving health after a stem cell transplant from a donor. It focuses on women's health issues after the transplant.
Hear when a new Graft Vs Host Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.