Study of AFA-281 for chronic low back pain
Part of Brain & nervous system, Pain clinical trials.
This trial tests an experimental medicine called AFA-281 for people with long-term low back pain caused by a pinched nerve in the lower spine. It aims to see if the drug is safe and can reduce pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old
- You have had low back pain for at least 3 months, caused by a pinched nerve in your lower back (at levels L4, L5, or S1)
- You have had an MRI or CT scan in the last year that rules out other spine problems
- Your average pain level is between 4 and 9 out of 10 at the start of the study
- You are willing to stop taking all current pain medications for 2 weeks before and during the study
- You are not pregnant, breastfeeding, or planning to become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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