Clin2
NCT06651333Possibly a fitRecruiting

Brain scans during opioid addiction treatment

Drug Use DisorderOpioid DependenceOpioid-Related DisordersOpioid UseOpioid Abuse

Part of Mental health clinical trials.

This study uses brain scans to understand how methadone or buprenorphine treatment affects the brain, with the goal of helping people stay in treatment and avoid relapse. You would need to be recently started on one of these medications and be able to undergo MRI scans.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
240 people
Ages
18 years to 50 years
Study type
Observational

Who can take part

  • You started methadone or buprenorphine treatment within the last year.
  • You are eligible for an MRI scan (no metal implants, pacemakers, or similar).
  • You can commit to attending study visits.
  • You do not have severe mental health issues like psychosis, mania, or active suicidal thoughts.
  • You do not have a history of intellectual disability, developmental disorder, or neurological disease, or a head injury with loss of consciousness over 30 minutes.
  • You do not have unstable medical conditions that could interfere with participation.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05336188Enrolling by invitation
Smartphone help to prevent relapse in opioid use disorder

This study looks at whether a smartphone-based program can help people avoid relapse from opioid use disorder. Some participants may also do brain scans to better understand the brain changes behind relapse prevention.

Little Rock, Arkansas
NCT06207162Recruiting
Brain scans and methadone treatment for opioid recovery

This study uses MRI scans over time to track brain changes in people with opioid use disorder who recently started methadone treatment. You can help researchers understand recovery patterns if you are early in your methadone journey and can commit to repeated visits.

New Haven, Connecticut
NCT07800520Recruiting· Phase 1
Brain imaging study for people with opioid use disorder

This study uses a special brain scan (PET) and MRI to look at how a protein in the brain, called CB1 (part of the body's natural pain and reward system), changes when people start treatment for opioid use disorder. It may help doctors understand how buprenorphine works and improve addiction treatments.

New Haven, Connecticut
NCT06440577Recruiting
Brain scan study of craving and choice in opioid use

This study uses brain scans (MRI) to understand how craving affects decision-making in people with opioid use disorder. It compares their brain activity to healthy volunteers, which may lead to better treatments.

Piscataway, New Jersey
NCT05683184Recruiting· Phase 1
Brain imaging study for opioid use disorder

This study uses brain scans to understand opioid use disorder better. If you have opioid addiction, you might be eligible to help researchers learn more about how the brain is affected.

New Haven, Connecticut
NCT06800703Recruiting
Opioid use, pain, and the brain

This study uses brain scans (MRI) to understand how pain affects people with opioid use disorder or regular opioid use, compared to healthy volunteers. It aims to find better ways to treat both pain and opioid addiction.

New Haven, Connecticut

Hear when a new Opioid Dependence trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.