Brain scan study of craving and choice in opioid use
Part of Mental health clinical trials.
This study uses brain scans (MRI) to understand how craving affects decision-making in people with opioid use disorder. It compares their brain activity to healthy volunteers, which may lead to better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and able to read and understand English at a 6th grade level or above.
- If you have opioid use disorder (OUD), you must have used opioids (heroin or painkillers) for at least 12 months and be getting treatment (like buprenorphine or methadone) as an outpatient.
- If you are a healthy volunteer, you cannot have used any illegal drugs (other than nicotine) or have a history of problematic alcohol use beyond college/military, and you cannot have taken certain brain medications in the last 6 weeks.
- You cannot have certain metal in your body, severe claustrophobia, or be pregnant (because an MRI is involved).
- You cannot have had a serious head injury with loss of consciousness over 30 minutes, seizures, or a history of intellectual disability or schizophrenia.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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