Volulyte fluid for heart protection during abdominal surgery
Part of Digestive system, Heart & circulation clinical trials.
This study tests a special IV fluid called Volulyte 6% given before, during, and after major abdominal surgery. The goal is to see if it is safe and helps protect the heart and blood vessels in people who are at higher risk of heart problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 45 years old or older.
- You are scheduled for major abdominal surgery that will last at least 2 hours and need general anesthesia.
- You plan to stay in the hospital at least overnight.
- You have at least one risk factor, such as being 65 or older, having heart or blood vessel disease, diabetes, smoking history, obesity (BMI ≥30), or certain abnormal blood test results.
- You do not have serious kidney, liver, or heart problems, bleeding disorders, or any condition that would make it unsafe for you to receive the study fluid.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of IV fluids (a starch solution vs. a balanced salt solution) to see which one better protects kidneys after heart surgery. It is for adults having planned heart surgery who do not have severe kidney problems.
This trial is testing a special fluid called succinylated gelatin (a type of colloid) given during surgery to help maintain blood volume. It is for people having planned surgery lasting less than 6 hours and who are in generally good health, without major heart, liver, or kidney problems.
This study looks at how the fluid used to fill the heart-lung machine affects the body's chemistry and recovery in patients having heart surgery. It may help doctors choose the best fluid for better outcomes after bypass surgery.
This trial compares two types of fluids (crystalloids and colloids) given during anesthesia for TAVR, a minimally invasive heart valve replacement. It aims to find which fluid better maintains blood pressure and heart function during the procedure.
This trial tests whether using a heart ultrasound before surgery can help doctors better manage your blood volume. If you are having surgery under general anesthesia and have a higher risk of heart problems, this study may help improve your safety.
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Hear when a new Perioperative Volume Replacement trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.