Clin2
NCT06668727Possibly a fitRecruiting

Testing a new antibody for hepatitis B safety

Hepatitis B

Treatments studied

Part of Digestive system, Infections clinical trials.

This trial tests an experimental antibody treatment for people with chronic hepatitis B who have been on antiviral medication for at least 6 months. It aims to see if the antibody is safe and can help control the virus.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • You have had hepatitis B for at least 6 months and have been on antiviral pills for at least 6 months.
  • Your hepatitis B virus is undetectable in your blood (DNA below the test's limit).
  • You have not been treated with any hepatitis B antibody before.
  • You do not have other active infections like HIV, hepatitis C, or hepatitis delta.
  • You do not have advanced liver scarring (fibrosis) or certain liver lesions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05856890Recruiting· Phase 1
Test antibody treatment for chronic hepatitis B

This Phase 1 trial tests HepB mAb19, an antibody medicine, in adults with chronic hepatitis B. The goal is to see how it works and how safe it is in people whose hepatitis B is controlled on current antiviral treatment.

New York, New York
NCT04843852Recruiting· Phase 1
Test vaccine added to hepatitis B treatment

This early-phase study tests whether a hepatitis B vaccine (with an added ingredient to boost the immune response) can safely help people with long-term hepatitis B who are already on antiviral therapy. It is mainly looking at safety and how the immune system responds.

Baltimore, Maryland
NCT07610772Recruiting· Phase 1
Safety study of a new hepatitis B antibody for hepatitis D

This early-stage trial tests whether a new monoclonal antibody (a lab-made protein that fights viruses) is safe and effective in people with chronic hepatitis D infection. Hepatitis D only occurs in people who also have hepatitis B, and this new treatment may help control the virus.

Aarhus
NCT06216470Recruiting· Phase 2
Testing an antibody treatment for chronic hepatitis B

This study tests a new antibody treatment (VIR-3434) for chronic hepatitis B. It aims to see if the antibody can help your immune system control the virus, potentially allowing you to stop your current antiviral medication later.

Toronto, Ontario
NCT07709520Recruiting· Phase 2
Testing a new hepatitis B treatment in adults

This trial tests a new treatment (GST-HG131&141 tablets) versus a placebo for people with chronic hepatitis B. It aims to see if the treatment can better control the virus in those already on stable therapy.

Beijing
NCT03038802Not yet recruiting· Phase 1/Phase 2
Study vaccine treatment for long-term hepatitis B infection

This trial tests an experimental vaccine therapy to help control or possibly cure chronic hepatitis B. It is designed to see whether the treatment is safe and how well it affects the hepatitis B virus in adults.

Adelaide, South Australia

Hear when a new Hepatitis B trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.