Study of Tune-401 for chronic hepatitis B
Part of Digestive system, Infections clinical trials.
This study tests a new medicine, Tune-401, for adults with chronic hepatitis B who are already on a daily antiviral pill. The goal is to see if it is safe and can reduce the virus in your body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chronic hepatitis B (a long-term infection with the hepatitis B virus).
- You are currently taking a daily antiviral pill for hepatitis B (like tenofovir or entecavir).
- You are between 18 and 75 years old.
- Your body mass index (BMI) is at least 18.5.
- Your liver blood tests (ALT/AST) are below 1.5 times the normal limit, and your bilirubin is normal or near normal.
- You do not have another type of liver disease besides hepatitis B (like fatty liver disease or alcoholic liver disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called GST-HG141 for people with chronic hepatitis B whose virus is still active despite taking standard antiviral pills. It aims to see if the new drug can better control the virus.
This trial tests a new treatment (GST-HG131&141 tablets) versus a placebo for people with chronic hepatitis B. It aims to see if the treatment can better control the virus in those already on stable therapy.
This study tests a new drug, GST-HG131, for people with chronic hepatitis B who are already on stable treatment. It aims to see if the drug is safe and reduces the virus further.
This study tests a new combination of medicines to help your immune system control the hepatitis B virus, with the goal of stopping the need for long-term treatment. It may be an option for people who have taken or are currently taking hepatitis B medications.
This trial is for people who have already completed a previous study of the drug GST-HG141 (Nairevir) and are now continuing with the same drug plus a nucleoside analog (a standard antiviral). It aims to see how safe and effective this combination is over a longer period.
This trial tests an experimental medicine called EPI-003 for people with chronic hepatitis B. It aims to see if the drug can help control the virus better and maybe lead to a functional cure.
Hear when a new Chronic Hepatitis B trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.