Medication before root canal to reduce pain
Part of Mouth & dental, Pain clinical trials.
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled for a root canal on a lower back tooth (molar).
- You have a tooth with a painful, inflamed nerve (irreversible pulpitis) but no infection at the tip of the root.
- You have not taken any painkillers or other medications for pain recently.
- You do not have any major health conditions (like diabetes, heart disease, etc.).
- You are not allergic to the study medications (trypsin-chymotrypsin, ibuprofen, paracetamol).
- You are not pregnant, and your tooth is restorable with fully developed roots.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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