Testing YOLT-204 for blood transfusions in beta-thalassemia
Part of Blood & lymphatic clinical trials.
This study tests an experimental drug called YOLT-204 to see if it is safe and can help people with transfusion-dependent beta-thalassemia need fewer blood transfusions. It is for adults aged 18 to 35 who have a specific type of thalassemia and are otherwise healthy enough for the trial.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 35 years old.
- You have been diagnosed with transfusion-dependent beta-thalassemia, but not the beta0/beta0 type.
- You have a good performance status (able to take care of yourself, score of at least 70 on the Karnofsky scale).
- Your heart, lungs, liver, and kidneys are working normally based on blood tests and heart scan.
- You have not had a stem cell transplant or prior gene therapy.
- You are willing to come for regular visits and follow long-term.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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