Metformin before chemoradiation for esophageal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests if taking metformin (a diabetes pill) before standard chemoradiation can make esophageal cancer respond better. You take metformin for 2 weeks before starting standard treatment, and doctors will check your tumor with two endoscopies to see how it changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have esophageal or gastro-esophageal junction adenocarcinoma that is surgically removable.
- You are scheduled to receive chemoradiation before surgery.
- You have adequate blood cell counts and kidney/liver function.
- You are willing to have two research endoscopies (camera tests).
- You do not have diabetes, do not take diabetes medications, and are not allergic to metformin.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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