Triptorelin test for diagnosing delayed puberty
Treatments studied
Part of Hormones & metabolism clinical trials.
This study uses a hormone called triptorelin to help doctors find the cause of delayed or stalled puberty in teenagers and young adults. The goal is to see if this medicine can clearly tell whether the problem is in the brain or elsewhere in the body.
Summary written for real people, not researchers, by Clin2.
Who can take part
- For female patients: age 13 or older with very early or no breast development (Tanner stage 1 or 2), or stopped developing for at least a year, or no period by age 15.
- For male patients: age 13.5 or older with testicles smaller than the size of a medium grape (less than 5 cc), or puberty that has stopped for at least a year.
- If you are taking hormone replacement therapy (like estrogen or testosterone), you must stop it for a certain period before the test (2 months for pills/patches, 3 months for monthly shots, 7 months for long-acting shots).
- You cannot have other known causes of delayed puberty, such as untreated thyroid problems, very low weight (BMI under 18), high prolactin levels, or conditions like Cushing's, uncontrolled diabetes, or celiac disease without a gluten-free diet.
- If you have a history of a brain tumor, you can join only if the tumor is in remission and at least one year has passed since finishing radiation therapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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