Clin2
NCT06698666Possibly a fitRecruiting

Can statins help treat depression?

Major Depressive DisorderMDD

Treatments studied

Part of Mental health clinical trials.

This trial tests if adding a statin (a cholesterol-lowering medicine) to your current depression treatment improves symptoms. It is for adults aged 20 to 45 with mild to moderate depression who are not already taking a statin.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
145 people
Ages
20 years to 45 years
Study type
Interventional

Who can take part

  • You are between 20 and 45 years old.
  • You have been diagnosed with major depressive disorder that is mild to moderate.
  • Your depression treatment has been stable for at least 2 weeks (except dose changes).
  • You are not currently taking statins, corticosteroids, or immune-modulating drugs.
  • You are not pregnant, breastfeeding, or using hormonal birth control (if female).
  • You have no history of bipolar disorder, psychotic disorders, or alcohol dependence.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07115329Recruiting· Phase 2
Testing Zelquistinel for major depression

This study tests a new oral medication called Zelquistinel (taken as a tablet) against a placebo for treating major depressive disorder. Researchers want to see if it can reduce depression symptoms, especially when other antidepressants haven't been tried or haven't worked.

Phoenix, Arizona
NCT06547489Recruiting· Phase 2
Testing zelquistinel for major depression

This study tests whether zelquistinel, an investigational drug, can reduce symptoms of major depressive disorder (a type of clinical depression). It is for people who are currently experiencing a moderate to severe depressive episode and are not taking other antidepressants.

Birmingham, Alabama
NCT04637620Recruiting· Phase 2
NMDA-based treatment study for major depression

This Phase 2 trial tests whether an NMDA-targeted treatment can improve symptoms of major depressive disorder (MDD). You may be able to join if your depression diagnosis and symptom score fit, and you meet several safety and study-following requirements.

Taichung
NCT06828887Recruiting· Phase 2
Testing LV232 capsules for major depression

This trial tests a new medicine called LV232 for people with moderate to severe depression. Researchers want to find the best dose and check if it works safely.

Shanghai
NCT06699966Not yet recruiting· Phase 4
Anti-inflammatory treatment for major depressive episodes

This trial tests whether anti-inflammatory drugs can help reduce symptoms of depression. If you are currently having a major depressive episode and have tried other treatments, this study may offer a new option.

NCT06860958Recruiting· Phase 3
Adding roflumilast to antidepressants for depression

This study tests if adding roflumilast, a medicine that reduces inflammation, can help people with major depression feel better when taken with their current antidepressant. It is for adults with moderate to severe depression.

Tanta

Hear when a new Major Depressive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.