Anti-inflammatory trial for depression
Treatments studied
Part of Mental health clinical trials.
This study tests whether two anti-inflammatory drugs, celecoxib and minocycline, can help treat depression. You may join if you have moderate to severe depression and are not at high risk for certain medical conditions or drug interactions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with major depressive disorder or bipolar depression and are currently in a major depressive episode.
- Your depression is at least moderate, based on a score of 29 or higher on a standard depression scale.
- You are not allergic to celecoxib, minocycline, or related medications, and you have not had a bad reaction to aspirin or other NSAIDs.
- You do not have a history of heart attack, heart disease, liver or kidney problems, stomach bleeding, or anemia.
- You are not taking certain medications that could interact with the study drugs without your doctor's approval.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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