Anti-inflammatory treatment for major depressive episodes
Treatments studied
Part of Mental health clinical trials.
This trial tests whether anti-inflammatory drugs can help reduce symptoms of depression. If you are currently having a major depressive episode and have tried other treatments, this study may offer a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have a diagnosis of major depressive disorder or bipolar depression and be currently in a major depressive episode.
- You must have at least moderate depression, as measured by a specific rating scale.
- You must not be allergic to celecoxib, minocycline, tetracyclines, sulfonamides, aspirin, or other NSAIDs.
- You must not have a history of heart attack, heart disease, liver problems, kidney problems, stomach bleeding, or ulcers.
- You must not be at high risk for suicide, and you must be able to stop certain medications before starting the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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