Clin2
NCT06700603Possibly a fitNot yet recruiting

Second-line combination treatment for irinotecan-treated pancreatic cancer

Pancreatic Cancer

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new combination of chemotherapy drugs for people whose pancreatic cancer has progressed after prior irinotecan treatment. The goal is to see if this new combination can help shrink tumors or slow the cancer's growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
48 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have a confirmed diagnosis of pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer).
  • Your cancer must have spread (advanced or metastatic) and you must have already tried a chemotherapy regimen that included irinotecan, and it stopped working.
  • You must have had no more than 3 prior cancer treatment regimens.
  • You need to have at least one tumor that can be measured on imaging (like a CT scan).
  • You must be in generally good physical condition (ECOG score 0-1), meaning you can do most daily activities with little or no help.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06578052Recruiting
Irinotecan liposome with capecitabine for advanced pancreatic cancer

This trial tests a combination of two chemotherapy drugs (irinotecan liposome and capecitabine) for people with pancreatic cancer that has spread or cannot be removed by surgery and has gotten worse after initial treatment. The goal is to see if this combination can help slow the disease.

Shenzhen, Guangdong
NCT06361316Recruiting
Liposomal irinotecan with chemo after pancreatic cancer surgery

This trial tests a combination of three chemotherapy medicines (liposomal irinotecan, oxaliplatin, and tegafur) given after surgery to remove pancreatic cancer. The goal is to see if this treatment helps prevent the cancer from coming back.

Nanjing, Jiangsu
NCT06375473Recruiting
Study of irinotecan liposome for pancreatic cancer

This study looks at how well a specific type of chemotherapy called irinotecan hydrochloride liposome works in people with pancreatic cancer. Researchers want to understand its effects in real-world settings, which may help doctors choose the best treatment for patients.

Hefei, Anhui
NCT06370754Not yet recruiting· Phase 1/Phase 2
A new immunotherapy for advanced pancreatic cancer

This trial tests a new kind of immunotherapy for pancreatic cancer that has not been removed by surgery or has spread. It aims to see if the treatment can help shrink or control the cancer, and you may be eligible whether you have had previous chemotherapy or not.

Shanghai, Shanghai Municipality
NCT06259058Not yet recruiting· Phase 1/Phase 2
Radiation plus chemo for borderline resectable pancreatic cancer

This trial tests whether giving radiation therapy before a combination of two chemotherapy drugs (NALIRIFOX) is better than chemotherapy alone for people with pancreatic cancer that is on the edge of being removable. The goal is to see if adding radiation helps shrink the tumor enough to make surgery possible and improve outcomes.

NCT06513455Not yet recruiting· Phase 1/Phase 2
Chemotherapy combination for untreated pancreatic cancer

This trial tests a combination of three chemotherapy drugs (irinotecan liposome, albumin-bound paclitaxel, and gemcitabine) as a first treatment for pancreatic cancer that hasn't spread. It aims to see if the combination can shrink tumors and improve survival with manageable side effects.

Hear when a new Pancreatic cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.