Study of an investigational drug for generalized anxiety disorder
Treatments studied
Part of Mental health clinical trials.
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a formal diagnosis of moderate to severe generalized anxiety disorder (GAD).
- Your anxiety symptoms need to be significant, as measured by a standard questionnaire (HAM-A score of 22 or higher).
- You need to have tried at least two standard anxiety medications (like paroxetine, venlafaxine, duloxetine, escitalopram, or buspirone) for at least 6 weeks and not gotten adequate relief.
- You cannot have tried and failed more than 3 of these medications in the past.
- You cannot have bipolar disorder, schizophrenia, or other psychotic disorders.
- You cannot be at significant risk for suicide or have recent suicidal behavior.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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