Testing HX301 for advanced high-grade glioma
Part of Cancer clinical trials.
This trial tests an experimental drug called HX301 for people with high-grade gliomas (fast-growing brain tumors). It is for patients whose tumor has come back after temozolomide chemo, or for those with newly diagnosed glioblastoma that has been surgically removed. The study aims to see if HX301 can help control the tumor.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have a high-grade glioma (WHO grade III or IV) that has come back after at least one round of temozolomide chemo, OR you have a newly diagnosed glioblastoma that has been surgically removed.
- Your doctor expects you to live at least 12 more weeks.
- You are physically active enough to take care of yourself (KPS score of 70 or higher).
- You can take low doses of dexamethasone (a steroid) – 5 mg or less per day – to control brain swelling.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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