Clin2
NCT06706986Possibly a fitEnrolling by invitation

Global registry for people with HIV who failed newer integrase inhibitors

HIVTherapy Failure

Part of Infections clinical trials.

This trial is a registry for people with HIV whose virus is no longer fully controlled by certain newer medications (integrase inhibitors). It aims to collect data to better understand why these treatments stop working and how to improve future care.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
250 people
Ages
Any age
Study type
Observational

Who can take part

  • You have HIV-1 and have been on HIV medications for at least 6 months.
  • Your virus was not controlled (viral load above 50 copies/mL twice, or above 200 copies/mL once) while on a medication called a second-generation integrase inhibitor.
  • Your doctor knows the details (start and stop dates, doses) of your current and past integrase inhibitor treatments.
  • A test showing your virus's genetics is available, or you can provide a blood sample taken when the treatment stopped working.
  • You have not skipped your HIV medications for 2 weeks or more just before the viral load test.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02437526Enrolling by invitation
Testing an HIV treatment pause to see if cure is possible

This study looks at whether some people with HIV can keep the virus controlled even if they temporarily stop HIV medicines (an “analytic treatment interruption”). If you qualify, it may help researchers learn what it would take for an HIV cure.

Rochester, Minnesota
NCT06805656Recruiting· Phase 2
Trial to reduce HIV reservoirs aiming for treatment-free remission

This study tests whether a combination approach, including a drug called nicotinamide (a form of vitamin B3) and other strategies, can reduce the hidden HIV reservoir enough to allow a temporary pause in antiretroviral therapy without the virus rebounding. It is for people who have well-controlled HIV and strong immune systems.

São Paulo, São Paulo
NCT07579247Not yet recruiting· Phase 1/Phase 2
Immune Checkpoint Inhibitors for Hard-to-Treat HIV Infections

This trial tests a new type of drug that helps your immune system fight serious infections that haven't improved with standard treatments in people with HIV. The drug works by releasing a 'brake' on your immune cells so they can fight infections better.

Shanghai, Shanghai Municipality
NCT06127290Recruiting
HIV treatment study for people in Eastern Europe and Russia

This study looks at how well newer HIV medicines work in people starting treatment for the first time in Eastern Europe and Russia. It also checks for drug resistance to find better treatment strategies.

Cologne
NCT05728996Recruiting
Study of early HIV to guide future care

This study follows people with a very recent HIV infection and collects blood and other samples to learn more about the infection soon after it starts. It may help researchers better understand early HIV and improve future treatments.

Amsterdam, North Holland
NCT06842706Not yet recruiting
HIV drug resistance study for people with viral failure

This study looks for drug-resistant HIV strains in people whose virus is not fully controlled by their current treatment. It aims to help doctors understand why the virus is still detectable.

Hear when a new HIV trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.