Stopping HIV treatment with antibody therapy
Part of Immune system & allergy, Infections clinical trials.
This trial tests whether a combination of powerful antibodies (bNAbs) can help control HIV after stopping standard HIV treatment. Participants will pause their daily HIV medications while receiving these antibodies, and doctors will closely monitor their immune system and virus levels. It's for people who are already well-controlled on HIV treatment and have participated in a specific earlier study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have completed a specific earlier NIAID study (MCA-1034) and finished your follow-up visits 12 to 24 weeks ago.
- You need to be on HIV treatment (ART) with a very low viral load (under 50 copies) for at least 48 weeks, without a break longer than 7 days.
- Your current CD4 count (immune cells) must be at least 400, and CD4 percentage at least 15%.
- You must be willing to switch to a different type of HIV medication if you're currently on an NNRTI-based regimen, for at least 4 weeks before stopping ART.
- If you can become pregnant, you must agree to use a highly effective contraception method from the start until ART is restarted and viral load is undetectable again.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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