Bacterial decolonization with angiography during sarcoma surgery
Part of Cancer clinical trials.
This trial tests whether using antibiotics and special imaging during surgery can improve outcomes for people with soft tissue sarcoma in the leg who are receiving radiation before surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a newly diagnosed soft tissue sarcoma in your leg (at or below the hip bone).
- You are well enough to be up and about for at least some of the day (ECOG score 0-2).
- You are eligible for surgery to remove the tumor and for radiation therapy beforehand.
- If you could become pregnant, you must have a negative pregnancy test within 28 days before starting radiation.
- You are not allergic to the antibiotics or disinfectants used in the study.
- You do not have an active skin condition or a tumor larger than 12.6 inches.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a shorter course of radiation (just 5 days) before surgery for soft tissue sarcoma. The goal is to see if a brief, high-dose radiation schedule works as well as or better than the usual longer course—and may be more convenient for you.
This trial tests combining anlotinib (a targeted therapy), doxorubicin (chemotherapy), and radiation given before surgery to shrink high-grade soft tissue sarcomas. The goal is to make the tumor easier to remove and improve outcomes.
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