Kidney transplant with thymus from a newborn donor
Part of Immune system & allergy, Kidney & urinary clinical trials.
This study is testing a new way to help the body accept a kidney transplant without needing lifelong anti-rejection drugs. It involves transplanting a small piece of the donor's thymus (a gland that helps the immune system) along with the kidney, to train the body to see the new kidney as part of itself.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are getting both a kidney and a thymus transplant (the thymus is a small gland that helps train your immune system) from the same donor.
- Your blood type must be compatible with the donor's blood type.
- You have had an Epstein-Barr virus (EBV) infection in the past (most adults have), and your body shows signs of it.
- You have not had a blood transfusion before.
- Your heart, liver, and blood-forming system are working normally.
- You do not have certain kidney diseases that are likely to come back after transplant, such as FSGS or certain types of glomerulonephritis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medicine called TNX-1500 that may help prevent the body from rejecting a new kidney. It is for people who are already waiting for a kidney transplant and aims to make the transplant more successful.
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
This trial tests if a special stem cell treatment (using your own stem cells) can reset your immune system so you can accept a kidney from a deceased donor, even if you have very high antibody levels that make it hard to find a match. It's for people who have been waiting a long time and haven't had a transplant offer.
This study tests a combined approach for kidney transplant patients: standard living-donor kidney transplant plus an added “stem cell” component taken from the same sibling donor. It aims to improve transplant outcomes by trying to better control the immune response and reduce complications.
This trial tests a blood test that may help monitor kidney transplant health by detecting signs of rejection earlier. It aims to see if using this blood test can lead to better long-term outcomes for transplant recipients.
This Phase 2 study tests a combined treatment—kidney transplant plus stem cell–based immune therapy—to help the body accept the new kidney with less immune attack. You may be able to take part if you have a matching sibling donor and meet key safety and health requirements.
Hear when a new Kidney Transplant trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.