Nimotuzumab plus immunotherapy and chemo for esophageal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study tests a new combination of drugs for advanced esophageal cancer. It adds an antibody (nimotuzumab) and an immunotherapy (sintilimab) to standard chemotherapy, aiming to improve how well treatment works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have squamous cell cancer of the esophagus that cannot be removed with surgery or has spread to other parts of the body.
- You have not had any previous treatment for your cancer, or if you did, it ended more than 6 months ago.
- You have at least one tumor that can be measured on a CT or MRI scan.
- Your overall health is good enough that you can take care of yourself (ECOG score 0 or 1).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests adding the targeted drug nimotuzumab to standard chemotherapy and radiation for people with esophageal cancer that cannot be removed by surgery. It may help shrink the tumor or stop it from growing further.
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This trial tests a combination of an immunotherapy drug (tislelizumab) with standard chemotherapy given before and after surgery for esophageal cancer. It aims to see if this approach can improve treatment outcomes for patients with a certain stage of the disease.
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