Clin2
NCT06718647Possibly a fitNot yet recruiting

Low-dose enzalutamide for advanced prostate cancer

Prostate Cancer Metastatic Disease

Part of Cancer, Kidney & urinary clinical trials.

This study looks at how well a lower dose of the medication enzalutamide works and how tolerable it is for men with advanced prostate cancer. The goal is to see if a lower dose can still help while reducing side effects.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
150 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have been diagnosed with prostate cancer that has spread to other parts of the body (called metastatic).
  • You took the drug enzalutamide between August 1, 2014, and December 31, 2023.
  • You are 18 years or older.
  • You have given permission (signed a consent form) to be part of the study.
  • You do not have a serious heart condition, such as a recent stroke or heart attack, uncontrolled high blood pressure, or heart failure.
  • You did not die within one month of starting enzalutamide.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06126731Recruiting· Phase 1/Phase 2
Antibiotics plus enzalutamide for advanced prostate cancer

This trial tests whether adding specific antibiotics (amoxicillin, metronidazole, vancomycin, ciprofloxacin) to enzalutamide can help treat advanced prostate cancer that has stopped responding to other treatments. It aims to see if changing gut bacteria can make the cancer therapy work better.

Bellinzona
NCT07512076Not yet recruiting· Phase 2
Finding the right dose of enzalutamide for older men with prostate cancer

This study tests whether older men (75+) with advanced prostate cancer need a different dose of enzalutamide than younger patients. Enzalutamide is a hormone therapy that slows prostate cancer growth. The trial will help doctors give the safest, most effective dose for elderly patients.

Toronto, Ontario
NCT04986423Recruiting· Phase 2
Add ZEN003694 to enzalutamide for resistant prostate cancer

This Phase 2 study tests whether adding ZEN003694 to enzalutamide works better than enzalutamide alone in men whose prostate cancer has spread and is no longer controlled by hormone lowering treatments. It focuses on people who either did not respond well to abiraterone (poor responders) or did respond (responders), then compares outcomes between treatment groups.

Los Angeles, California
NCT07104643Not yet recruiting· Phase 1/Phase 2
New drug plus enzalutamide for advanced prostate cancer

This trial tests a new drug (TYK-00540) combined with enzalutamide for men whose prostate cancer has spread and is no longer responding to standard hormone therapy. It may be an option if you have tried only one other newer hormone treatment and it failed.

Hangzhou, Zhejiang
NCT06130995Recruiting· Phase 1
Relugolix and enzalutamide for high-risk prostate cancer

This trial tests a combination of two oral drugs, relugolix and enzalutamide, in men with high-risk prostate cancer that hasn't spread to distant parts of the body. The goal is to see if this treatment can help control the cancer before or alongside local therapies like surgery or radiation.

Oklahoma City, Oklahoma
NCT04363164Recruiting· Phase 2
Testosterone then enzalutamide to stop prostate cancer spread

This Phase 2 trial tests whether giving testosterone first, then enzalutamide (a prostate cancer hormone-blocking pill), can slow or prevent worsening metastatic prostate cancer. It is designed for men whose cancer progressed despite ongoing hormone-suppression treatment.

San Diego, California

Hear when a new Prostate Cancer Metastatic Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.