Clin2
NCT06727773Likely a fitRecruiting

Memantine and exercise to protect thinking during chemo for breast cancer

Breast CancerLocally Advanced Breast CancerCognitive ImpairmentCognitive DeclineCognitive ChangeBreast Cancer Stage IBreast Cancer Stage IIBreast Cancer Stage III

Treatments studied

Part of Cancer, Mental health, Skin clinical trials.

This study tests whether a medicine called memantine combined with a structured exercise program can help protect your thinking and memory during chemotherapy for breast cancer. It may also help understand how these treatments work in the body.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
90 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are female and at least 18 years old.
  • You have been diagnosed with stage I, II, or III breast cancer.
  • Your doctor has recommended chemotherapy as part of your treatment plan.
  • You can sign up for this study before your third round of chemotherapy.
  • You speak English.
  • You do not have a severe memory problem, a recent heart attack, or a condition that prevents you from exercising safely.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04616300Recruiting
Exercise program to support brain function during breast cancer chemo

This trial studies whether a structured exercise program can help protect or improve thinking and memory in people with breast cancer while they are starting chemotherapy after surgery. It may help with “chemo brain” by targeting brain function during treatment.

Toronto, Ontario
NCT07372144Not yet recruiting· Phase 3
Creatine for brain health during breast cancer chemo

This study tests whether taking creatine (a natural supplement) during and after chemotherapy can help protect your memory and thinking skills in women with early-stage breast cancer. You would receive either creatine or a placebo pill and be followed with cognitive tests.

São Paulo, São Paulo
NCT06027632Recruiting
Brain training at home to help with chemo brain after breast cancer treatment

This study tests a supervised computer-based mental exercise program to help reduce memory and thinking problems after chemotherapy. It is for people who finished chemo for early-stage breast cancer and still have bothersome mental fogginess.

Bordeaux
NCT05305092Recruiting
Study of memory and thinking in early breast cancer

This study checks how breast cancer affects memory and thinking before other treatments start. It may help doctors better understand cognitive changes and who is most at risk.

Xi'an, Shaanxi
NCT07017530Not yet recruiting
Exercise and brain training for breast cancer brain fog

This study tests whether combining cognitive training with physical exercise can help women with breast cancer who experience memory or thinking problems. It is for women who are currently receiving or have recently completed chemotherapy.

Badajoz, Badajoz
NCT07447050Recruiting· Phase 2
Riluzole to Prevent Chemo-Related Cognitive Problems

This pilot study tests whether the drug riluzole can help prevent the thinking and memory problems (often called 'chemobrain') that some people experience during chemotherapy. If you are about to start a chemo regimen containing an anthracycline or platinum drug, you may be able to join.

Orange, California

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.