Steroids with chemoradiation for thymoma that can't be removed
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests if adding a steroid (methylprednisolone) to standard chemotherapy and radiation helps people with thymoma that cannot be fully removed by surgery or has come back. The goal is to see if this combination works better at controlling the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of thymoma called AB, B1, B2, or B3 (the lab confirmed this).
- Your tumor can be measured on scans and is located in the chest or neck but cannot be removed surgically, or it has come back after treatment.
- You are between 18 and 70 years old.
- You are in good enough health to be up and about (able to do light work or daily activities).
- You have not had radiation to your chest before.
- You are not pregnant or breastfeeding, and you do not have certain health problems like active infections, recent heart attack, or bleeding disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at adding radiation after a complete surgery to remove a thymoma (a tumor from the thymus) at stages II or III. It may help lower the chance the cancer comes back by treating leftover microscopic disease after surgery.
This trial tests a shorter course of radiation (hypofractionated radiotherapy) for people with thymoma or thymic carcinoma. It aims to see if fewer, larger doses of radiation are safe and effective for treating these tumors.
This trial tests a shorter course of radiation therapy (fewer, larger doses) given after surgery for thymic tumors. The goal is to reduce the chance of the tumor returning while keeping side effects manageable.
This trial combines surgery (burning away the tumor) with heated chemotherapy given directly into the chest to treat thymus gland tumors that have spread to the lining of the lung or chest wall. The goal is to remove the visible tumor and wash the area with heated chemo to help delay or prevent it from coming back.
This trial tests giving radiation therapy before surgery for a type of thymus gland tumor (thymoma) that has grown into nearby tissues but has not been treated yet. The goal is to see if this approach can make the tumor removable and improve outcomes.
This trial tests whether adding an immunotherapy drug called adebrelimab to chemotherapy and radiation before surgery can help shrink thymic cancer and improve outcomes. It is for people with locally advanced thymic carcinoma that can potentially be removed with surgery.
Hear when a new Thymoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.