Oral insulin for type 2 diabetes management
Part of Hormones & metabolism clinical trials.
This trial tests an oral insulin capsule (ORMD-0801) for people with type 2 diabetes. It aims to see if the capsule can help control blood sugar safely, possibly offering an alternative to injections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 50 years old or older.
- You have had type 2 diabetes for at least 6 months and your A1C (average blood sugar) is between 7.2% and 10.0% at the screening visit.
- You are currently taking 1 to 3 diabetes pills (like metformin, glipizide, or similar) and have been on a stable dose for at least 3 months.
- Your body mass index (BMI) is 28 or lower, and your weight has been stable (no more than 11 pounds gained or lost) in the last 3 months.
- Your kidneys work well enough, with an eGFR of 30 or higher.
- You have not used insulin injections in the last 3 months.
- You do not have a history of severe low blood sugar or a condition called hypoglycemia unawareness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an experimental tablet to see if it can help control blood sugar in people with type 2 diabetes. It may be an option for those who are already on metformin or managing with diet and exercise.
This trial tests a new once-daily tablet (elecoglipron) against a placebo to see if it can help improve blood sugar control in adults with type 2 diabetes who are already on insulin. It may offer an additional treatment option to help manage your diabetes.
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
This study tests a new medication called HM15275 to help control blood sugar in people with type 2 diabetes. The trial will check if the medication works well and is safe when added to diet, exercise, or metformin treatment.
This trial tests an experimental daily tablet for adults with type 2 diabetes who are not currently on any diabetes medication. It aims to see if the tablet can safely lower blood sugar levels over time.
This early-stage study tests whether a new oral (swallowed) form of insulin called SCD0503 works as well as regular injected insulin in men with type 1 diabetes. Researchers will also check how food affects how your body absorbs the oral insulin.
Hear when a new Type 2 Diabetes Mellitus trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.