Clin2
NCT06732245Possibly a fitNot yet recruiting

Testing a new drug plus tirzepatide for weight loss

Obesity and Overweight

Treatments studied

Part of Hormones & metabolism clinical trials.

This study tests a new drug, NA-931, combined with an existing weight-loss medication (tirzepatide) to see if they work well and are safe for adults who are overweight or obese. It may help you lose weight and improve health conditions related to excess weight.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
224 people
Ages
19 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • Your body mass index (BMI) must be 30 or higher, or 27 or higher if you also have a weight-related condition like high blood pressure or high cholesterol.
  • Your weight must have been stable (within about 11 pounds) for the last 3 months, and it must be less than 330 pounds.
  • You must have tried to lose weight before (for example, through diet or exercise) without success.
  • You must not be taking any other weight-loss medication now or in the past 30 days.
  • If you are a woman who can become pregnant, you must use specific birth control methods and have negative pregnancy tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07868354Not yet recruiting· Phase 1
Switching to a new weight-loss medicine from tirzepatide

This study tests how well adults with overweight or obesity, with or without type 2 diabetes, tolerate switching from their current weight-loss medication (tirzepatide) to a new medicine called zenagamtide. It may help you understand if this new option is easier on your stomach.

Glendale, California
NCT06439277Recruiting· Phase 3
Tirzepatide for teens with obesity and related health problems

This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.

Los Angeles, California
NCT07245771Recruiting· Phase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide

This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).

Melbourne, Victoria
NCT07671391Not yet recruiting· Phase 2
Experimental injection plus tirzepatide for weight loss in obesity

This study tests an experimental medicine (LAE102) combined with a known weight-loss drug (tirzepatide) to see if it helps people with obesity lose more weight safely. You would receive the study drug or a placebo (a dummy shot), and the goal is to find a better way to manage weight.

NCT07099742Not yet recruiting
Tirzepatide for weight loss in adults with obesity

This study tests a medicine called tirzepatide to see if it helps people with overweight or obesity lose weight, whether or not they also have type 2 diabetes. Tirzepatide is given as an injection and works on hormones that control appetite.

Comilla
NCT07298915Not yet recruiting· Phase 3
Exercise and tirzepatide for better weight and health

This study tests whether combining a weight-loss medication called tirzepatide (also known as Mounjaro) with a supervised exercise program helps people lose weight and improve their overall health. You'll be in the study for about four months, and you'll get support and monitoring.

Charlottesville, Virginia

Hear when a new Obesity and Overweight trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.