Tirzepatide for teens with obesity and related health problems
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be an adolescent (age 12–17) with obesity (BMI at or above the 95th percentile for your age and sex).
- You must have at least two weight-related health problems, such as high blood pressure, prediabetes, or high triglycerides.
- You must have tried to lose weight through diet at least once before, but it didn't work.
- You cannot have had weight-loss surgery in the past or plan to have it during the study.
- You cannot have type 1 or type 2 diabetes, or a blood sugar level (HbA1c) above 6.4%.
- You cannot have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
This study tests a medicine called tirzepatide to see if it helps people with overweight or obesity lose weight, whether or not they also have type 2 diabetes. Tirzepatide is given as an injection and works on hormones that control appetite.
This trial tests if tirzepatide is more effective than standard obesity treatments for adults who have a BMI between 30 and 35 and one weight-related health condition, but do not have diabetes. The goal is to help you lose weight.
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
This study tests a medication called tirzepatide for people with type 1 diabetes who also have overweight or obesity. Tirzepatide may help with weight loss and blood sugar control, and you'll use a continuous glucose monitor throughout the study.
This study tests a medication called tirzepatide (a daily injection) to help people who haven't lost enough weight after weight-loss surgery. If you fit the criteria, the medication may help you lose more weight healthily.
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.