Treatment
Tirzepatide clinical trials
We’re tracking 85 recruiting studies that include Tirzepatide, each written for real people, not researchers, below.
Recruiting studies
- NCT07574723Recruiting
Tirzepatide dosing strategy to manage side effects in obesity
This study tests a new medication called tirzepatide, given at carefully adjusted doses, to help people with obesity lose weight while reducing unwanted side effects. Tirzepatide is a newer injectable medicine that helps control appetite and blood sugar.
Kuwait CityAges 18–100 - NCT07423247RecruitingPhase 4
Tirzepatide for weight loss in kidney transplant patients
This trial tests if tirzepatide can help people who have had a kidney transplant and are still overweight lose weight. It may be an option if you have had your transplant at least a year ago, your kidney function is stable, and your body mass index is 27 or higher.
TehranAges 18 years+ - NCT07191873RecruitingPhase 4
Tirzepatide for treating high pressure in the brain
This trial tests if tirzepatide can help lower the pressure inside your skull caused by a condition called Idiopathic Intracranial Hypertension. It's designed for people with a BMI of 30 or higher who have swelling of the optic nerve.
Durham, North CarolinaAges 18–60 - NCT05553093RecruitingPhase 4
Tirzepatide vs insulin for diabetes and brain effects
This study tests how tirzepatide and insulin glargine affect blood sugar, fat metabolism, and brain function in adults with type 2 diabetes. It may help researchers learn which treatment changes diabetes-related body and brain processes.
Nanjing, JiangsuAges 18–75 - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Tucson, ArizonaAges 6–11 - NCT07803744RecruitingPhase 1
Study of tirzepatide for type 1 diabetes with overweight
This study tests a weekly injection called tirzepatide in people with type 1 diabetes who are overweight or have obesity. The goal is to see if it helps with blood sugar control and weight loss when added to insulin therapy.
Miami, FloridaAges 18–70 - NCT07777575RecruitingPhase 4
Exercise and medication for weight loss while preserving muscle
This study tests whether a type 2 diabetes medication (tirzepatide) combined with a supervised resistance training (weight lifting) program helps prevent muscle loss while losing weight. You will either receive the medication or a placebo, and all participants will follow a diet and exercise plan.
München, BavariaAges 18–60 - NCT07734870RecruitingPhase 2
Tirzepatide for treating scarring hair loss (CCCA)
This study tests whether tirzepatide (Mounjaro) can help treat a specific type of scarring hair loss called CCCA. It is for people whose hair loss is still active and who are not taking diabetes or weight-loss medications.
Baltimore, MarylandAges 18–80 - NCT05708859RecruitingPhase 4
Tirzepatide to slow plaque buildup in coronary arteries
This trial studies tirzepatide to see if it can slow the progression of coronary artery plaque in people with type 2 diabetes. It uses special heart CT scans to track changes over time.
Torrance, CaliforniaAges 40–80 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT07693608Enrolling by invitationPhase 2
Tirzepatide for weight loss in stimulant use disorder
This trial tests whether a weekly injection called tirzepatide (a diabetes and weight-loss medication) can help people with obesity and stimulant use disorder reduce stimulant use and lose weight. It aims to see if treating both conditions together improves outcomes.
Dallas, TexasAges 18–65 - NCT05912621RecruitingPhase 2
Tirzepatide for fat-related body dysfunction in overweight adults
This Phase 2 study tests whether tirzepatide can improve how your body handles fat (especially in people with overweight or obesity) and reduce fat-related “lipotoxicity.” It may help with body fat function and related health markers, but you must meet specific health and medication rules.
Palo Alto, CaliforniaAges 18–70 - NCT07602699RecruitingPhase 2
Tirzepatide to Help People Quit Smoking
This study tests whether tirzepatide, a medication that helps with weight and blood sugar, can also help people quit smoking. You'd receive the medication plus standard quitting support (nicotine patches or gum and a quit-smoking app) over several months.
Los Angeles, CaliforniaAges 21–65 - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT07573163RecruitingPhase 2
Tirzepatide after adrenal surgery for mild cortisol condition
This trial tests if tirzepatide can help with weight and blood pressure after you have surgery to remove an adrenal gland that's making too much cortisol. It may be a good option if you still have health issues like high blood pressure or obesity after surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65 - NCT07521631RecruitingPhase 2
HDM1005 versus Tirzepatide for weight management in obese adults
This study tests whether a new injectable medication called HDM1005 works as well as tirzepatide (a GLP-1 drug) for weight loss in adults with obesity but no diabetes. Both medications work similarly in the body to help control appetite and weight.
ShanghaiAges 18–65 - NCT07481747RecruitingPhase 3
Weekly injection for weight loss in adults with obesity
This trial tests a once-weekly injection (tirzepatide) versus a placebo to help people who are obese or overweight with related health conditions lose weight. You may qualify if you have tried to lose weight through diet before, but have not been successful.
Shenzhen, GuangdongAges 18 years+ - NCT07387796Recruiting
Brain and behavior changes with tirzepatide stop and restart
This study looks at how your brain and behavior change when you stop and then restart the weight loss drug tirzepatide. It will help researchers understand what happens during treatment breaks.
Dallas, TexasAges 18–70 - NCT07373834Recruiting
Tirzepatide and muscle health in women with obesity
This study tests whether tirzepatide, a medication for weight management, affects muscle health in women with obesity. It may help if you are looking for a treatment that preserves muscle while losing weight.
LjubljanaAges 18–50 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07293325Recruiting
Semaglutide and Tirzepatide for slowing aging in adults with obesity
This trial tests if two newer weight-loss medications, semaglutide and tirzepatide, can help slow the aging process in adults with obesity. It compares the drugs to each other and to a placebo to see which might offer anti-aging benefits beyond weight loss.
HangzhouAges 18–75 - NCT07284511RecruitingPhase 2/Phase 3
Tirzepatide for automatic blood sugar control in type 1 diabetes
This trial tests if adding tirzepatide (a once-weekly injection) to an automated insulin pump system (Control-IQ) helps adults with type 1 diabetes better manage their blood sugar. It requires using the Tandem Control-IQ pump and counting carbohydrates.
Montreal, QuebecAges 18 years+
What Tirzepatide is being studied for
Conditions with recruiting Tirzepatide studies.
Common questions
- Are there clinical trials studying Tirzepatide?
- Yes. Clin2 currently lists 85 recruiting studies that include Tirzepatide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Tirzepatide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Tirzepatide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Tirzepatide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.