Testing a new treatment for muscle loss in sarcopenia
Part of Brain & nervous system clinical trials.
This trial tests a new approach to treat sarcopenia (age-related muscle loss) by targeting a protein called HIF-1α. It compares older adults with sarcopenia to younger adults without it, all of whom are having hip or knee surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 35 years old (without sarcopenia) or over 65 (with sarcopenia).
- Your body mass index (BMI) is between 18 and 30.
- If you have sarcopenia, you are scheduled for hip surgery due to arthritis, a past hip problem, a broken hip, or a hip replacement revision.
- If you do not have sarcopenia, you have an ACL injury requiring surgery.
- You are not taking medicines or have conditions that affect muscle or bone.
- You are not pregnant or breastfeeding (if in the control group).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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