Early intensive cholesterol-lowering study for acute coronary syndrome
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether starting strong cholesterol-lowering treatment early in the hospital can improve outcomes for people with acute coronary syndrome (a serious heart condition like a heart attack or unstable angina). It may help if you have high LDL cholesterol.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are currently in the hospital for a heart attack or unstable angina (a type of chest pain that is a warning sign for a heart attack).
- Your LDL cholesterol level is high enough: at least 1.8 mmol/L if you are already on a statin, or at least 2.6 mmol/L if you have not taken a statin in the last 4 weeks.
- You have not received a PCSK9 inhibitor (a type of cholesterol-lowering injection) in the last 3 months.
- You do not have severe liver or kidney problems, and you are not a transplant patient.
- You are not pregnant, breastfeeding, or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests an educational program to help people understand and lower their LDL ('bad') cholesterol after a heart-related event. It aims to improve awareness and encourage the use of cholesterol-lowering treatments.
This study tests whether adding an extra cholesterol-lowering drug (bempedoic acid) to the usual treatment soon after a heart attack or related event can lower 'bad' cholesterol more effectively. It may help reduce the risk of future heart problems.
This study tests whether starting a cholesterol-lowering injection (a PCSK9 inhibitor) early after a heart attack can slow or shrink the buildup of plaque in other heart arteries that are not the one that was stented. If you have two other arteries with mild blockages, this treatment might help prevent future heart problems.
This trial compares two very low LDL-cholesterol targets (below 1.0 vs 1.0-1.39 mmol/L) using extra medications (PCSK9 inhibitors) to see which is safer and better for people at extremely high risk of heart attacks or strokes.
This trial tests whether giving a powerful cholesterol-lowering drug (PCSK9 inhibitor) very early after a heart attack can help prevent further heart problems. It is for people who have had a recent heart attack and have blockages in more than one heart artery.
This study tests whether a newer cholesterol-lowering injection, given early after a heart attack, helps keep the plaque in your arteries stable and reduces future risk. It compares the new medicine added to your usual statin treatment.
Hear when a new Acute Coronary Syndromes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.