A new device to treat aortic dissection and prevent growth
Part of Heart & circulation clinical trials.
This study tests a new device made of a special material that is injected into the false lumen (an abnormal channel) of an aortic dissection to prevent the aorta from growing larger. It is for people with a type B aortic dissection who have not been treated before or who have had prior treatment and now need further help.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You need to have a type B aortic dissection (a tear in the lower part of the aorta) that has not been treated for the main tear, OR you have had a prior procedure to treat the main tear and now have a false lumen (an abnormal channel) that needs treatment.
- Your dissection must have started more than 2 weeks ago (not in the acute phase).
- You must not have any untreated tears near the left subclavian artery (a major blood vessel) or other blocking issues in your blood vessels.
- You must not have a connective tissue disorder like Marfan or Ehlers-Danlos syndrome.
- You must have adequate kidney function (creatinine level not above 2.5 mg/dL) and no recent stroke, heart attack, or major heart surgery within the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new polymer device to close the false lumen (an extra channel) in the aorta for people with type B aortic dissection. It may prevent the aorta from growing and reduce the risk of complications.
This trial tests a new device made of shape-memory polymer that is placed into the false lumen (abnormal blood channel) of an aortic dissection to block blood flow and prevent the aorta from growing. It's for people with type B aortic dissections who either haven't had treatment for the primary tear yet, or have had that tear treated but now need to address the false lumen.
This trial tests a new device (WeFlow-EndoPatch) to seal small tears in the aorta after previous dissection repair. It may be an option if you have 1 or 2 small tears in your descending aorta and are generally healthy enough for a catheter procedure.
This trial tests a special stent graft for people with a type B aortic dissection that needs a new blood flow path to the left subclavian artery. The device is placed in the aortic arch to repair the tear and keep blood flowing normally.
This trial tests a special plug (WeFlow-EndoSeal) placed into the false channel of a type B aortic dissection to help seal it. It is for people who are already getting a stent-graft and aims to improve the repair.
This study tests a combination of a stent (a small mesh tube) plus a procedure to block the false channel (the abnormal blood flow path) in patients with a type B aortic dissection that is not an emergency. The goal is to help the aorta heal and prevent future problems.
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