Exercise and a new medication for schizophrenia or bipolar disorder
Part of Mental health clinical trials.
This study tests whether a combination of a daily medication (olanzapine-samidorphan) and a structured exercise program can help people with schizophrenia, schizoaffective disorder, or bipolar disorder improve their health and well-being.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have been diagnosed with schizophrenia, schizoaffective disorder, or bipolar I/II disorder.
- Your weight has been stable (less than 5% change) for at least 3 months.
- You have not taken opioid painkillers in the past 14 days and do not plan to during the study.
- You do not have diabetes or a history of diabetes.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether clozapine works better for people whose illness fits a specific “biotype-1” pattern. It may help reduce ongoing symptoms, but it also requires close safety monitoring.
This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.
This study tests whether combining physical activity with being in green outdoor spaces can reduce the tough symptoms of schizophrenia, like feeling flat or unmotivated. It's designed for people whose negative symptoms are not going away.
This trial tests a new combination tablet (olanzapine-samidorphan) for adults with schizophrenia. It aims to see if it helps control symptoms while potentially reducing weight gain, which can be a side effect of some schizophrenia medicines.
This study looks at how exercise affects brain function in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can improve brain-related outcomes alongside standard treatment.
This Phase 3 study tests a treatment aimed at reducing unhealthy weight gain in teens with schizophrenia or bipolar I disorder, using changes in BMI (a height-and-weight measure). It may help families who are concerned about weight changes that can happen with some psychiatric medicines.
Hear when a new Schizophenia Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.