Study of H syndrome and inflammation

This study is for people with hemophagocytic lymphohistiocytosis (HLH), a condition where the immune system becomes overactive. Researchers want to collect medical data and blood samples to better understand HLH and find better ways to diagnose and treat it.

This study follows people with or suspected Hyper-IgE syndrome (a rare immune disorder causing repeated infections and skin problems) to understand how the condition develops, how best to manage it, and which genes are involved. Researchers also welcome healthy relatives of patients to help identify genetic patterns.

This study looks at people with histiocytic disorders, which are rare conditions where certain immune cells grow too much. It aims to learn more about these disorders to improve diagnosis and treatment.

This study looks at how certain body “inflammatory genes” behave in people with hidradenitis suppurativa. It may help researchers understand what drives this condition and how future treatments could be targeted.

This research study investigates Hermansky-Pudlak Syndrome (HPS), a rare genetic condition affecting blood clotting and skin color. Researchers are looking for people with HPS or their family caregivers to participate in clinical evaluations and questionnaires to better understand the condition.

This study follows adults who have findings that suggest HLH, a serious immune problem. It may help doctors better understand the condition by tracking patients over time and comparing symptoms and test results.